Paper of the Week: sCD28, sCD80, sCTLA-4, and sBTLA Are Promising Markers in Diagnostic and Therapeutic Approaches for Aseptic Loosening and Periprosthetic Joint Infection

Paper of the Week: sCD28, sCD80, sCTLA-4, and sBTLA Are Promising Markers in Diagnostic and Therapeutic Approaches for Aseptic Loosening and Periprosthetic Joint Infection

Jubel J.M., Randau T. M., Becker-Gotot J., Scheidt S., Wimmer M. D., Kohlhof H., Burger C., Wirtz D. C., Schildberg F. A. Front Immunol. 2021 Aug 6; 12: 687065. doi: 10.3389/fimmu.2021.687065 Summary by Diana Fernández-Rodríguez, MD Aseptic loosening, peri-implant fractures, and prosthetic joint infection (PJI) are the most frequently described complications after arthroplasty.1–3 Macrophage-mediated osteolysis…

Paper of the Week: A Back Table Ultraviolet Light Decreases Environmental Contamination During Operative Cases

Paper of the Week: A Back Table Ultraviolet Light Decreases Environmental Contamination During Operative Cases

Jason M Jennings, Todd M Miner, Roseann M Johnson, Aviva K Pollet, Anna C Brady, Douglas A Dennis Am J Infect Control. 2021 Oct 2; S0196-6553(21)00640-4doi: 10.1016/j.ajic.2021.09.020 Summary by Farideh Najafi, MD Many modifiable and nonmodifiable risk factors increase infection rates after joint arthroplasty surgeries. One of the important modifiable risk factors is the operating…

Paper of the Week: Outcomes of Primary Total Knee Arthroplasty Following Septic Arthritis of the Native Knee: A Case-Control Study

Paper of the Week: Outcomes of Primary Total Knee Arthroplasty Following Septic Arthritis of the Native Knee: A Case-Control Study

Bettencourt, J. W., Wyles, C. C., Fruth, K. M., Osmon, D. R., Hanssen, A. D., Berry, D. J., & Abdel, M. P. JBJS, 103(18), 1685-1693, 2021doi: 10.2106/JBJS.20.01678 Summary by Nareena Imam, BA Rates of same-joint periprosthetic joint infection (PJI) after total knee arthroplasty (TKA) in patients with a history of septic arthritis of the native…

Paper of the Week: Leukocyte Esterase Versus ICM 2018 Criteria in the Diagnosis of Periprosthetic Joint Infection

Paper of the Week: Leukocyte Esterase Versus ICM 2018 Criteria in the Diagnosis of Periprosthetic Joint Infection

Chisari E, Yacovelli S, Goswami K, Shohat N, Woloszyn P, Parvizi J. The Journal of Arthroplasty. 2021;36(8):2942-2945.e1. doi: 10.1016/j.arth.2021.03.006 Summary by Saad Tarabichi MD Periprosthetic joint infection (PJI) is a catastrophic complication and a significant cause of implant failure after total joint arthroplasty (TJA).1 Recent studies demonstrate that PJI incurs substantial costs to patients while…

Paper of the Week: Intraosseous Regional Prophylactic Antibiotics Decrease the Risk of Prosthetic Joint Infection in Primary TKA: A Multicenter Study

Paper of the Week: Intraosseous Regional Prophylactic Antibiotics Decrease the Risk of Prosthetic Joint Infection in Primary TKA: A Multicenter Study

Ben Parkinson MBBS, FRACS (Orth), FAOrthA, Peter McEwen MBBS, FRACS (Orth), FAOrthA, Matthew Wilkinson MBBS, FRACS (Orth), FAOrthA, Kaushik Hazratwala MBBS, FRACS (Orth), FAOrthA, Jorgen Hellman B.med, FRACS (Orth), FAOrthA, Heng Khan MBBS, Andrew McLean MBBS, Yash Panwar MBBS, Kenji Doma PhD, BSpExcSci(Hons), MClinExPhys(Rehab), CSCS, AEP, NSCAM, ESSAM, Andrea Grant BSpExSci Clin Orthop Relat Res….