Authors: Tiziana Ascione, Ali Oliashirazi, Yi Rong Zeng
(A) At present, there is no consensus regarding the optimal follow-up schedule for patients being treated for PJIs and no specifi research discussing this topic. In the absence of evidence, we recommend that the patients should be followed at 6 weeks postoperatively, 3 months, 6 months, 12 months, and annually thereafter, with adjustments being made based on individual circumstances. Inflammatory
markers should be measured on a weekly basis after resection arthroplasty.
(B) As of now there is no study to assess the frequency with which the biomarkers need to be checked during the course of a two-stage exchange for PJIs. Most of the available studies have checked the available diagnostic battery of the tests, including serum erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) as well as synovial fluid white blood cell (WBC) count, polymorphonuclear (PMN) and leucocyte esterase (LE) at least once prior to the second stage (reimplantation). However, there is no unified protocol that provides recommendations on the timing of these tests. Future studies in this field are required to guide the orthopaedic community and help form a consensus.
LEVEL OF EVIDENCE: (A) Consensus, (B) Consensus
DELEGATE VOTE: Agree: 85%, Disagree: 7%, Abstain: 8% (Super Majority, Strong Consensus)