Can short term (two weeks or less) antibiotic treatment be considered following resection arthroplasty for chronic periprosthetic joint infections (PJIs)?

Can short term (two weeks or less) antibiotic treatment be considered following resection arthroplasty for chronic periprosthetic joint infections (PJIs)?

Authors: Henk Eijer, Brian de Beaubien, Ian Stockley, Adam Kratky, Bernard Kessler, Kimberly E. Martin, Chris Ferry, Michael J. Petrie, Kerri Bell

RECOMMENDATION: Yes. Following an aggressive debridement and insertion of an antibiotic-loaded cement spacer (ALCS) or beads, a shortterm course of less than two weeks of systemic antibiotic therapy can be considered. Several studies show promising results with infection eradication rates comparable to when a much longer course of antibiotic treatment is used.

LEVEL OF EVIDENCE: Limited

DELEGATE VOTE: Agree: 64%, Disagree: 32% Abstain: 4% (Super Majority, Weak Consensus)

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