Does the use of allografts alter the recommended duration of prophylactic antibiotics?

Authors: Heinz Winkler, Oleg Safir, Sergio Rudelli

RECOMMENDATION: No. Allografts are avascular materials that are prone to contamination and may serve as a scaffold for bacterial colonization and biofilm production, similar to a prosthesis or osteosynthetic material. However, it is difficult to establish a causal relationship between the use of an allograft and subsequent infection. Thus, there is no evidence to support the use of extended antibiotic prophylaxis.

LEVEL OF EVIDENCE: Limited

DELEGATE VOTE: Agree: 91%, Disagree: 6%, Abstain: 3% (Super Majority, Strong Consensus)

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