Is there a need for antibiotic therapy following irrigation and debridement of patients with acute shoulder periprosthetic joint infection (PJI) caused by a virulent organism (e.g., methicillin-resistant Staphylococcus aureus (MRSA), methicillin-sensitive Staphylococcus aureus (MSSA) or E. coli)?

Authors: William Levine, Paul Pott inger, Sandra Bliss Nelson, Iván Encalada, John Itamura
RECOMMENDATION: In the absence of high level data, we propose that patients with acute PJI of shoulder caused by virulent organisms, such as MRSA, MSSA or E. coli, receive postoperative antibiotics. The optimal antibiotic, route of administration and duration of treatment are unknown and should be individualized after consultation with infectious disease specialists.
LEVEL OF EVIDENCE: Consensus
DELEGATE VOTE: Agree: 100%, Disagree: 0%, Abstain: 0% (Unanimous, Strongest Consensus)