Is there a role for measuring synovial biomarkers for diagnosis of infected total ankle arthroplasty (TAA)?

Authors: Khaled Emara, John M. Embil

RECOMMENDATION: Based on the hip and knee arthroplasty literature, measuring synovial biomarkers may play a role in the diagnosis of infected TAA. The diagnosis of periprosthetic joint infection (PJI) in the sett ing of a TAA can be confirmed with cultures, provided that a plausible pathogen is recovered in the context of a compatible clinical picture. In the absence of a positive culture, synovial biomarker analysis may help in establishing the diagnosis.

LEVEL OF EVIDENCE: Moderate

DELEGATE VOTE: Agree: 92%, Disagree: 8%, Abstain: 0% (Super Majority, Strong Consensus)

FA-18