Is there a role for oral suppressive antimicrobial therapy in acute periprosthetic joint infection (PJI) in the sett ing of retained prostheses after initial intravenous (IV) therapy? Same duration as for lower extremity arthroplasty? Should it diff er by pathogen (e.g., methicillin-sensitive Staphylococcus aureus (MSSA) vs. methicillin-resistant S. aureus (MRSA))?

Authors: Joseph Abboud, Thomas Duquin, Michael Henry
RECOMMENDATION: While the role of debridement, antibiotics and implant retention (DAIR) in the treatment of acute prosthetic shoulder infection has not been well-studied, there is likely a role for oral suppressive antimicrobial therapy in the sett ing of retained infected shoulder prostheses after DAIR. There is no evidence to guide the optimal duration of treatment or if treatment should vary by organism.
LEVEL OF EVIDENCE: Limited
DELEGATE VOTE: Agree: 96%, Disagree: 0%, Abstain: 4% (Unanimous, Strongest Consensus)

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