Is there a role for postoperative antibiotic treatment for revision arthroplasty with subsequent unexpected positive cultures for a virulent organism (e.g., methicillin-resistant S. aureus (MRSA), methicillin-sensitive Staphylococcus aureus (MSSA) or E. coli)?

Authors: Edward Yian, Robert Tashjian, Henk Scheper
RECOMMENDATION: In aggregate, published studies do not clearly show superiority for prolonged antibiotic use over no prolonged antibiotic treatment in the sett ing of revision shoulder arthroplasty with subsequent cultures positive for virulent organisms. However, the data on this
specifi c clinical scenario is limited as the vast majority of unexpected positive cultures are with less virulent organisms (e.g., C. acnes, Coagulasenegative Staphylococcus (CNS)).
LEVEL OF EVIDENCE: Limited
DELEGATE VOTE: Agree: 96%, Disagree: 4%, Abstain: 0% (Unanimous, Strongest Consensus)

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