Is there a role for synovial fluid tumor necrosis factor-alpha (TNF-α) and interleukin (IL)-2 in the diagnosis of shoulder periprosthetic joint infection (PJI)?

Is there a role for synovial fluid tumor necrosis factor-alpha (TNF-α) and interleukin (IL)-2 in the diagnosis of shoulder periprosthetic joint infection (PJI)?

Authors: Joseph Iannoti, Victor Naula, Eric Ricchett i
RECOMMENDATION: There is a potential role for synovial fluid TNF-α and IL-2 in the diagnosis of shoulder PJI when interpreted in combination with other synovial fl uid markers. TNF-α and IL-2 may not be as useful individually.
LEVEL OF EVIDENCE: Limited
DELEGATE VOTE: Agree: 96%, Disagree: 0%, Abstain: 4% (Unanimous, Strongest Consensus)

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