Authors: Alex McLaren, Garth D. Ehrlich
RESPONSE: In vivo animal studies have demonstrated that interference with quorum sensing signals/molecules in some infections leads to decreased biofilm formation. There are contradictory results in Staphylococcus species. However, there are no clinical studies demonstrating this phenomenon.
LEVEL OF EVIDENCE: Limited
DELEGATE VOTE: Agree: 100%, Disagree: 0%, Abstain: 0% (Unanimous, Strongest Consensus)B9