Is undergoing a colonoscopy or upper gastrointestinal (GI) endoscopy after total joint arthroplasty (TJA) associated with an increased risk of surgical site infection/periprosthetic joint infection (SSI/PJI)? If yes, does antibiotic prophylaxis prior to a colonoscopy or upper GI endoscopy after TJA reduce the risk?

Authors: Nicolaas Budhiparama, Tricia Bravo, H. Hidayat, I. Lumban Gaol, N.N. Ifran, D.N. Utomo

RECOMMENDATION: Colonoscopy and upper GI endoscopy have the potential to cause transient bacteremia, though the evidence is limited to support an associated risk of SSI/PJI. There is no evidence that administration of antibiotics prior to GI procedures decreases the risk of SSI/PJI and
this practice should be avoided. Further research is needed to see if this practice may be benefi cial in selected or high-risk patients.

LEVEL OF EVIDENCE: Limited

DELEGATE VOTE: Agree: 84%, Disagree: 13%, Abstain: 3% (Super Majority, Strong Consensus)

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