Should factors like preoperative radiation, soft tissue vs. bone resection, presence of metal vs. structural allograft and other factors influence the dose and duration of antibiotic prophylaxis?

Authors: Rodolfo Capanna, Ivan Bohaček, Lorenzo Andreani

RECOMMENDATION: Unknown. Evidence and guidelines directing the prescription of prophylactic antibiotic regimens in musculoskeletal tumor surgery are lacking. Although long-term antibiotic prophylaxis may decrease the risk of deep infection, there is not sufficient evidence to recommend the use of anything other than routine antibiotic prophylaxis for patients undergoing major reconstruction.

LEVEL OF EVIDENCE: Limited

DELEGATE VOTE: Agree: 100%, Disagree: 0%, Abstain: 0% (Unanimous, Strongest Consensus)

112-1