Should operative treatment diff er in patients with systemic sepsis in the setting of periprosthetic joint infection (PJI)?

Authors: Antony Rapisarda, Tae-Kyun Kim, Salvador Rivero-Boschert
RECOMMENDATION: Yes. Patients with systemic sepsis in the sett ing of PJI should have surgical bioburden reduction, either with implant retention or resection of components (if indicated and safe), along with concurrent anti-microbial therapy. Reimplantation should be delayed until sepsis is resolved.
LEVEL OF EVIDENCE: Limited
DELEGATE VOTE: Agree: 79%, Disagree: 19%, Abstain: 2% (Super Majority, Strong Consensus)

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