Should patients with periprosthetic joint infections (PJIs) caused by Mycobacterium tuberculosis (TB) undergo the typical two-week antimicrobial holiday prior to reimplantation?

Should patients with periprosthetic joint infections (PJIs) caused by Mycobacterium tuberculosis (TB) undergo the typical two-week antimicrobial holiday prior to reimplantation?

Authors: Aree Tanavalee, Miguel Molano

RECOMMENDATION: There is no evidence supporting the two-week antimicrobial holiday before reimplantation. Patients with PJIs caused by TB do not need to have the two-week drug holiday.

LEVEL OF EVIDENCE: Consensus

DELEGATE VOTE: Agree: 88%, Disagree: 6%, Abstain: 6% (Super Majority, Strong Consensus)

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