Should the antibiotics placed in a cement spacer be tailored to the sensitivity of the infective organism?

Authors: Akos Zahar, Andrew Porteous, Viktor Janz, Ankit Varshneya, Vishwas Sharma

RECOMMENDATION: Antibiotics added to cement spacer during resection arthroplasty should be tailored towards the causative organism and its susceptibility. In case of culture negative periprosthetic joint infections (PJIs), consideration should be given to the addition of a broad-spectrum antibiotic to the cement spacer to cover the most potential pathogens causing PJI.

LEVEL OF EVIDENCE: Moderate

DELEGATE VOTE: Agree: 94%, Disagree: 3%, Abstain: 3% (Super Majority, Strong Consensus)