Should vancomycin powder be applied to the wound in patients undergoing spinal surgeries? Are there any potential harms associated with this practice?

Authors: Steven Schmitt , Christopher Kepler

RECOMMENDATION: Yes. Evidence suggests that vancomycin powder applied to the wound during spinal surgery reduces the risk of infection. However, the majority of studies lack a control arm and it is not known if vancomycin powder is better than antiseptic agents. There is insufficient evidence for or against the potential harm associated with this practice.

LEVEL OF EVIDENCE: Moderate

DELEGATE VOTE: Agree: 79%, Disagree: 14%, Abstain: 7% (Super Majority, Strong Consensus)

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