What antibiotic(s) should be used for low-energy open fractures? What antibiotic(s) should be used for high-energy open and grossly-contaminated fractures?

Authors: Rodrigo Pesantez, Cristina Suarez

RECOMMENDATION: 1. Antibiotic treatment targeting gram-positive organisms is recommended as soon as possible for all open fractures; low- and high-energy. 2. In high-energy or grossly-contaminated open fractures, additional antibiotics should be considered for gram-negative coverage.

LEVEL OF EVIDENCE: 1. Strong; 2. Limited

DELEGATE VOTE: Agree: 95%, Disagree: 0%, Abstain: 5% (Unanimous, Strongest Consensus)