What are the ideal strategies to prevent secondary and nosocomial contamination of open fracture wounds which are left open?

What are the ideal strategies to prevent secondary and nosocomial contamination of open fracture wounds which are left open?

Authors: Robert O’Toole, Nathan O’Hara

RECOMMENDATION: Data support local antibiotics and early wound closure to reduce contamination of open facture wounds. NOTE: The recommendation above was changed from the original version so the rationale below does not completely align with this recommendation. Please see Section 3:2, Question 2 for rationale for early wound closure. The rationale below regarding negative pressure wound therapy (NPWT) applies to Section 3:2, Question 4.

LEVEL OF EVIDENCE: Moderate

DELEGATE VOTE: Agree: 100%, Disagree: 0%, Abstain: 0% (Unanimous, Strongest Consensus)

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