What are the ideal strategies to prevent secondary and nosocomial contamination of open fracture wounds which are left open?

Authors: Robert O’Toole, Nathan O’Hara

RECOMMENDATION: Data support local antibiotics and early wound closure to reduce contamination of open facture wounds. NOTE: The recommendation above was changed from the original version so the rationale below does not completely align with this recommendation. Please see Section 3:2, Question 2 for rationale for early wound closure. The rationale below regarding negative pressure wound therapy (NPWT) applies to Section 3:2, Question 4.

LEVEL OF EVIDENCE: Moderate

DELEGATE VOTE: Agree: 100%, Disagree: 0%, Abstain: 0% (Unanimous, Strongest Consensus)

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