What are the recommendations regarding the route (intravenous (IV) vs. oral (PO)) and length of postoperative antibiotic treatment when a one-stage revision arthroplasty is performed for subacute/chronic shoulder periprosthetic joint infection (PJI) caused by a virulent organism (e.g., methicillin-sensitive Staphylococcus aureus (S. aureus), or MSSA, vs. methicillin-resistant S. aureus (MRSA), E. coli)?

Authors: Mandeep Virk, Mark Morrey
RECOMMENDATION: Intravenous antibiotics or intravenous followed by oral antibiotics are both reasonable options for one-stage revision shoulder arthroplasty for subacute/chronic shoulder PJI caused by a virulent organism. As there is no consensus on the route or duration, these treatment parameters should be selected in consultation with an infectious disease specialist.
LEVEL OF EVIDENCE: Limited
DELEGATE VOTE: Agree: 100%, Disagree: 0%, Abstain: 0% (Unanimous, Strongest Consensus)

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