What is the best method for anterior cruciate ligament (ACL) allograft sterilization to minimize the incidence of postoperative infections and mechanical weakening of the graft?

What is the best method for anterior cruciate ligament (ACL) allograft sterilization to minimize the incidence of postoperative infections and mechanical weakening of the graft?

Authors: Sam Oussedik, Sachin Tapasvi, Domenico Ravier, Ilaria Morelli, Shantanu Patil, M.K. Balaji

RECOMMENDATION: The best method for ACL allograft sterilization to minimize the incidence of postoperative infection and mechanical weakening of the graft is the use of irradiation (preferably less than 1.8 Mrad). Allografts should be harvested aseptically and fresh-frozen, whenever possible.

LEVEL OF EVIDENCE: Limited

DELEGATE VOTE: Agree: 100%, Disagree: 0%, Abstain: 0% (Unanimous, Strongest Consensus)

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