What is the minimum biofilm eradication concentration (MBEC) of anti-infective agents?

Authors: Jan Geurts, Williem Berend Schreurs, Jean-Yves Jenny

RESPONSE/RECOMMENDATION: The MBEC of antimicrobial agents is a measure of in vitro antibiotic susceptibility of biofilm producing infective organisms. It is dependent on the surface, medium and the exposure period to an antimicrobial agent. There are no standardized measurement parameters for MBEC. MBEC is currently a research laboratory value and lacks clinical availability. In the group’s opinion, there is value in
developing a clinically-validated MBEC assay.

LEVEL OF EVIDENCE: Consensus

DELEGATE VOTE: Agree: 100%, Disagree: 0%, Abstain: 0% (Unanimous, Strongest Consensus)

PRE-MEETING RATIONALE

B12