What is the most optimal antibiotic treatment for chronic osteomyelitis?

Authors: Stephen Kates, Edward Hendershot

RECOMMENDATION: Antiobiotic selection should be culture-specific, if possible. No clear evidence exists to suggest that longer duration of therapy (12 to 16 weeks) is superior to shorter duration (4 to 6 weeks). In addition, there is no evidence to support the proposition that intravenous (IV) antibiotic treatment is superior to oral treatment.

LEVEL OF EVIDENCE: Limited

DELEGATE VOTE: Agree: 96%, Disagree: 4%, Abstain: 0% (Unanimous, Strongest Consensus)

315