What is the optimal length of antibiotic treatment following debridement, antibiotics and implant retention (DAIR) for acute periprosthetic joint infections (PJIs)?

Authors: Jamie Lora-Tamayo, David Warren, Mikel Mancheno-Losa, Marius Arndt, Christian Lausmann, Marius Arndt

RECOMMENDATION: The optimal length of antibiotic treatment following DAIR remains relatively unknown as there is considerable heterogeneity regarding the length, dose and administration of treatment. A minimum of six weeks of antibiotic therapy seems to be sufficient in most cases of PJIs managed by DAIR-provided surgical treatment.

LEVEL OF EVIDENCE: Moderate

DELEGATE VOTE: Agree: 91%, Disagree: 8%, Abstain: 1% (Super Majority, Strong Consensus)

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