What is the optimal length of antibiotic treatment following debridement, antibiotics and implant retention (DAIR) for acute periprosthetic joint infections (PJIs)?

What is the optimal length of antibiotic treatment following debridement, antibiotics and implant retention (DAIR) for acute periprosthetic joint infections (PJIs)?

Authors: Jamie Lora-Tamayo, David Warren, Mikel Mancheno-Losa, Marius Arndt, Christian Lausmann, Marius Arndt

RECOMMENDATION: The optimal length of antibiotic treatment following DAIR remains relatively unknown as there is considerable heterogeneity regarding the length, dose and administration of treatment. A minimum of six weeks of antibiotic therapy seems to be sufficient in most cases of PJIs managed by DAIR-provided surgical treatment.

LEVEL OF EVIDENCE: Moderate

DELEGATE VOTE: Agree: 91%, Disagree: 8%, Abstain: 1% (Super Majority, Strong Consensus)

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