What is the recommended duration of antibiotics after a single-stage exchange for periprosthetic joint infections (PJIs)?

What is the recommended duration of antibiotics after a single-stage exchange for periprosthetic joint infections (PJIs)?

Authors: Sujith Konan, Lars Frommelt, Christian Lausmann, Thorsten Gehrke, Andrea Volpin

RECOMMENDATION: In the setting of single-stage exchange arthroplasty, intravenous antibiotics should be administered for 10-14 days followed by oral antibiotics. Generally, the overall duration of antibiotics of 4-6 weeks is sufficient.

LEVEL OF EVIDENCE: Limited

DELEGATE VOTE: Agree: 73%, Disagree: 23%, Abstain: 4% (Super Majority, Strong Consensus)

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