What is the role of molecular techniques for detection of pathogen deoxyribonucleic acid (DNA) (polymerase chain reaction (PCR) or next-generation sequencing) in patients with infected total ankle arthroplasty (TAA)?

Authors: Khaled Emara, Amiethab Aiyer, Ryan Rogero

RECOMMENDATION: Molecular techniques, particularly next-generation sequencing and the Ibis T5000 technology, have the potential to be used as an important adjunct in the diagnosis of bacterial infection following TAA, although sufficient clinical evidence is lacking.

LEVEL OF EVIDENCE: Limited

DELEGATE VOTE: Agree: 100%, Disagree: 0%, Abstain: 0% (Unanimous, Strongest Consensus)

FA-19